Fiona Bruce presents an hour of topical debate from West London with pre-recorded questions from Leeds and questions and comments from social media. On this week's panel: Grant Shapps MP, secretary of state for transport, Conservative; Anneliese Dodds MP, shadow chancellor of the exchequer, Labour; Jeane Freeman MSP, Scottish government health secretary, SNP; Sir Paul Nurse, chief executive of the Francis Crick Institute and former director of the Royal Society; and George Osborne, editor of the Evening Standard, former Conservative MP and chancellor of the exchequer, 2010-2016.